Construction of Nitrogen-Oxygen-Heterocycles via Copper-Free Click Reactions of Nitrile Oxides

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Kinetic Study of Reactions between Nitrile Oxides with Simple Cycloalkynes with DFT Method

In this study, reactions of the simple cycloalkynes with substituted Nitrile Oxides, by DFT method will be discussed. The investigation of the structural properties, theoretical thermodynamic and kinetic data, i.e., the activation free energies(DG*), the free energies changes of reaction(DrG) and rate constants of the reactions (k) in 298 K and effects of Electron-withdrawing and...

متن کامل

Construction of indole- and isoquinoline-fused nitrogen-containing heterocycles through copper-catalyzed multi-component reaction.

A copper-catalyzed synthesis of 2-(aminomethyl)indole through domino three-component coupling-cyclization has been developed. This reaction proceeds through Mannich-type coupling of 2-ethynylanilines, aldehydes, and secondary amines, followed by hydroamination. This indole formation was applicable to the synthesis of 4-methylene-2,3,4,9-tetrahyro-1H-pyrido[3,4-b]indoles and 5,6,7,8-tetrahydrobe...

متن کامل

Intramolecular alkoxycyanation and alkoxyacylation reactions: new types of alkene difunctionalizations for the construction of oxygen heterocycles.

Saturated oxygen heterocycles, such as tetrahydrofurans and dihydrobenzofurans, are important motifs in a myriad of biologically active compounds, including natural products and pharmaceutical targets. Therefore, there has been considerable interest in the development of new synthetic methods for the construction of these important structures. Many traditional approaches to the generation of th...

متن کامل

Synthesis of oxygen heterocycles via alkynyltungsten compounds*

This short review article covers some useful applications of alkynyltungsten compounds to the syntheses of complex lactones. Two types of cyclizations will be emphasized: (1) cycloalkenylation of tungsten-alkynol compounds with aldehydes to give α-alkylidene oxacarbeniums, further leading to α-alkylidene lactones and (2) intramolecular [3+2]-cycloaddition of epoxides to give bicyclic lactones. ...

متن کامل

Construction of cyclic enones via gold-catalyzed oxygen transfer reactions

During the last decade, gold-catalyzed reactions have become a tour de force in organic synthesis. Recently, the gold-, Brønsted acid- or Lewis acid-catalyzed oxygen transfer from carbonyl to carbon-carbon triple bond, the so-called alkyne-carbonyl metathesis, has attracted much attention because this atom economical transformation generates α,β-unsaturated carbonyl derivatives which are of gre...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Chinese Journal of Organic Chemistry

سال: 2014

ISSN: 0253-2786

DOI: 10.6023/cjoc201311044